p-Hydroxy-cinnamic acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

p-Hydroxycinnamic Acid 可抑制血小板活性，对于血栓素 B2 产生和脂多糖诱导的前列腺素 E2 产生的 IC50 分别为 371 μM、126 μM。

p-Hydroxycinnamic acid can inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.(In Vitro):p-Hydroxycinnamic acid (p-Coumaric acid), is a ubiquitous plant metabolite with antioxidant and anti-inflammatory properties. p-Hydroxycinnamic acid (500 μM and 1 mM) reduces ADP-induced platelet aggregation (55?2 (SE 4?01) % and 35?6 (SE 2?35) % relative to basal level, respectively). p-Hydroxycinnamic acid is able to modify platelet function, a shear-inducing device that simulates primary haemostasis. p-Hydroxycinnamic acid interferes also with arachidonic acid cascade, reducing thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation (IC50 371 and 126 μM, respectively).

p-Hydroxycinnamic acid (p-Coumaric acid), is a ubiquitous plant metabolite with antioxidant and anti-inflammatory properties. p-Hydroxycinnamic acid (500 μM and 1 mM) reduces ADP-induced platelet aggregation (55?2 (SE 4?01) % and 35?6 (SE 2?35) % relative to basal level, respectively). p-Hydroxycinnamic acid is able to modify platelet function, a shear-inducing device that simulates primary haemostasis. p-Hydroxycinnamic acid interferes also with arachidonic acid cascade, reducing thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation (IC50 371 and 126 μM, respectively).

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Endocrinology/Hormones

CaMK

Thromboxane A2 synthetase| PGE2

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7400-08-0

164.16

C9H8O3

>98% (HPLC)

DMSO : ≥ 100 mg/mL; 609.16 mM

OC(=O)\C=C\c1ccc(O)cc1

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(-20℃)

With Ice Pack

≥ 2 years